Centre for Natural Products Research and Drug Discovery (CENAR)

Our Services

"Pricing shown is per sample, per run."

Nuclear Magnetic Resonance (NMR)

User Type	Price
Internal	from RM 60 / sample
External	from RM 100 / sample

Full NMR Spectroscopy Service - Comprehensive NMR analysis featuring 1D, ¹H and ¹³C spectra, DEPT for carbon type differentiation, and 2D experiments including COSY, HMQC, and HMBC. Ideal for precise structural elucidation and molecular characterization of organic compounds..

Liquid Chromatography–Mass Spectrometry (LCMS)

User Type	Price
Internal	RM 150 / sample
External	RM 300 / sample

Our LCMS services provide highly sensitive and precise analytical solutions for the identification, quantification, and characterization of complex chemical mixtures. Utilizing advanced chromatographic separation coupled with mass spectrometric detection, our LCMS platform delivers comprehensive profiling of small molecules, peptides, proteins, metabolites, and pharmaceutical compounds.

High-Performance Liquid Chromatography (HPLC)

User Type	Price
Internal	RM 170 / sample
External	RM 250 / sample

Our HPLC services provide accurate, reliable, and high-resolution analysis for a wide range of chemical and biological compounds. Using state-of-the-art HPLC systems and validated methods, we offer both qualitative and quantitative analysis tailored to your specific application.

Gas Chromatography–Mass Spectrometry (GCMS)

User Type	Price
Internal	RM 110 / sample
External	RM 220 / sample

Our GCMS services offer precise and reliable analysis for the separation, identification, and quantification of volatile and semi-volatile compounds across a wide variety of sample types. Combining high-resolution gas chromatography with sensitive mass spectrometric detection, our GCMS platform enables comprehensive profiling and detailed chemical characterization.

Gas Chromatography–Fourier Transform Infrared (GC-FTIR)

User Type	Price
Internal	RM 70 / sample
External	RM 140 / sample

Our GC-FTIR services combine the powerful separation capabilities of gas chromatography with the molecular identification precision of infrared spectroscopy. This hybrid technique enables detailed qualitative and structural analysis of volatile and semi-volatile compounds in complex mixtures.

Fourier Transform Infrared Spectroscopy (FT-IR)

User Type	Price
Internal	RM 50 / sample
External	RM 80 / sample

We offer FT-IR services for rapid, accurate identification and characterization of materials. FT-IR is a powerful analytical tool used to determine the molecular composition and structure of a wide range of substances, including organic compounds, polymers, chemicals, pharmaceuticals, and unknown materials.

UV-Vis Spectroscopy (UV-Vis)

User Type	Price
Internal	RM 50 / sample
External	RM 50 / sample

Our UV-Vis services provide rapid, accurate, and non-destructive analysis of a wide range of samples by measuring their light absorption in the ultraviolet and visible regions of the electromagnetic spectrum. This technique is ideal for determining the concentration, purity, and chemical properties of substances in solution.

Sample Preparation (Plant) – Drying and Grinding

User Type	Price
Internal	from RM 100 / sample
External	from RM 150 / sample

Our plant sample preparation process involves controlled drying to reduce moisture content while preserving the integrity of bioactive compounds, followed by precise grinding to achieve uniform particle size. This preparation ensures optimal extraction efficiency and consistent analytical results.

Maceration Process

User Type	Price
Internal	RM 700 / sample
External	RM 750 / sample

We provide professional Maceration Extraction Services designed to gently extract valuable bioactive compounds from plant materials using controlled soaking techniques.

Drying and Concentration Services

User Type	Price
Internal	from RM 15 / sample
External	from RM 30 / sample

We provide specialized drying and concentration services to remove solvents and preserve bioactive compounds from plant extracts and other samples using advanced, low-temperature techniques.

Chromatography Purification & Isolation Services

User Type	Price
Internal	from RM 1250 / sample
External	from RM 1500 / sample

We offer expert chromatography services for the purification and isolation of target compounds from complex mixtures. Utilizing advanced chromatographic techniques, we deliver high-purity isolated substances tailored to your research or production needs.

Extraction of Essential Oil

User Type	Price
Internal	from RM 90 / sample
External	from RM 120 / sample

We specialize in Essential Oil Extraction using cutting-edge techniques to deliver pure, high-quality oils from a wide range of aromatic plants and botanicals.

Antioxidant Assays

User Type	Price
Internal	RM 150 / sample
External	RM 250 / sample

We offer a range of validated antioxidant assays to accurately measure the free radical scavenging and reducing power of natural extracts, compounds, and formulations. Our assays help determine the antioxidant potential critical for product development and quality control.

Antimicrobial Assays

User Type	Price
Internal	RM 250 / sample
External	RM 350 / sample

We provide comprehensive antimicrobial testing services to evaluate the effectiveness of natural extracts, compounds, and formulations against a wide range of microbial strains.

NMR SERVICE CHARGES - JEOL 500MHz (2025)

1 - PACKAGE PER SAMPLE

NO	PACKAGE	INTERNAL UM (RM)			EXTERNAL USER (RM)
NO	PACKAGE	1D (per hour)	2D (per hour)	Full Set	1D (per hour)	2D (per hour)	Full Set
1	Running sample only	80	100	300	150	220	500
2	Running + interpretation (report)	150	250	500	250	500	1,200
3	Running + interpretation (report) + consultation	200	400	800	300	600	1,700

Full Set - 1H, 13C, COSY, DEPT, HMQC & HMBC

2 - PACKAGE PER YEAR (WITH 25 HOURS PER MONTH)

NO	PACKAGE	INTERNAL UM (RM)	EXTERNAL USER (RM)
1	Running sample only	3,000	5,000
2	Running + interpretation (report)	6,000	8,000
3	Running + interpretation (report) + consultation	10,000	15,000

3 - SAMPLE PREPARATION

NO	SOLVENT	PRICE (RM)	SAMPLE PREP WITH NMR TUBE (RM)
1	CDCl₃	50	70
2	CD₃OD	60
3	D₂O	55
4	DMSO(d₆)	70
5	Acetone (d₆)	70

Extraction of Essential Oil

PACKAGE PER SAMPLE

Type of works	Description	Price (RM) - Internal	Price (RM) - External	Condition / number of sample
Solvent-Free Microwave Extraction (SFME)	A combination of microwave heating and dry distillation, performed at atmospheric pressure without added any solvent or water. Isolation and concentration of volatile compounds are performed by a single stage.	170	220	500g of sample for 30 mins
Hydrodistillation	Uses water or steam for the extraction of volatile compounds, mostly essential oils	90	120	300g of sample

Sample Preparation (Plant) – Drying and Grinding

PACKAGE PER SAMPLE

Type of works	Description	Price (RM) - Internal	Price (RM) - External	Condition / number of sample
Drying	Performed under regulated temperature and humidity to prevent degradation or loss of sensitive phytochemicals.	100	150	1 kg of sample
Grinding	Utilizes calibrated milling equipment to produce fine, homogeneous powders suitable for extraction or further analysis.	300	350	1 kg of sample

Maceration Process

PACKAGE PER SAMPLE

Type of works	Description	Price (RM) - Internal	Price (RM) - External	Condition / number of sample
Hexane	Ground samples soak in hexane to extracts compounds that dissolved in hexane (usually non-polar compound)	700	750	1 kg of sample
Ethyl Acetate / Dichloromethane	Extract sample will be partitioned ethyl acetate / dichloromethane to extracts compounds that dissolved in ethyl acetate / dichloromethane (usually medium polar compound)	700	750	1 kg of sample
Methanol	Extract sample will be partitioned methanol to extracts compounds that dissolved in methanol (usually polar compound)	700	750	1 kg of sample

Chromatography Purification & Isolation Services

PACKAGE PER SAMPLE

Type of works	Description	Price (RM) - Internal UM user	Price (RM) - External UM user	Condition / number of sample
Normal phase chromatography	stationary phase (Silica)	1250	1500	1 sample
Normal phase chromatography	stationary phase (Sephadex) - size exclusion chromatography	1750	2000	1 sample
Reverse phase chromatography	HPLC (C-18)	1250	1500	1 sample
Reverse phase chromatography	HPLC (C-8)	1250	1500	1 sample

Drying and Concentration Services

PACKAGE PER SAMPLE

Type of works	Description	Price (RM) - Internal UM user	Price (RM) - External UM user	Condition / number of sample
Rotary Evaporation (Rotavap)	Ideal for gentle solvent removal under reduced pressure, preserving heat-sensitive compounds with high efficiency.	50	70	1 sample in 500 ml of round bottom flask
Freeze Drying (Lyophilization)	Used for complete moisture removal by sublimation, yielding stable, dry powders ideal for long-term storage or formulation.	80	100	1kg of sample per day (including freezing)
Centrifugal Evaporator (MiVAC)	Rapid drying of small-volume samples under vacuum, suitable for volatile solvents and thermally sensitive materials.	15	30	1 sample in 10 ml of test tube

Antioxidant Assays

PACKAGE PER SAMPLE

Type of works	Description	Price (RM) - Internal UM user	Price (RM) - External UM user	Condition / number of sample
DPPH Radical Scavenging Assay	Measures the ability of compounds to donate hydrogen atoms or electrons to neutralize the stable DPPH free radical, indicating free radical scavenging activity.	150	250	1 sample with 3 replicates
ABTS Radical Cation Decolorization Assay	Evaluates antioxidant capacity by measuring the reduction of the blue-green ABTS⁺• radical cation to a colorless form in the presence of antioxidants.	150	250	1 sample with 3 replicates
FRAP (Ferric Reducing Antioxidant Power) Assay	Assesses the reduction of ferric (Fe³⁺) to ferrous (Fe²⁺) ions by antioxidants, reflecting their electron-donating capacity.	150	250	1 sample with 3 replicates
Beta-Carotene Bleaching Assay	Measures the ability of antioxidants to prevent the oxidative degradation of beta-carotene, indicating their capacity to inhibit lipid peroxidation and protect against oxidative damage.	150	250	1 sample with 3 replicates
Total Antioxidant Capacity (TOAC) Assay	Quantifies the overall antioxidant activity of a sample by evaluating its ability to neutralize a broad spectrum of reactive oxygen species, providing a comprehensive measure of antioxidant potential.	150	250	1 sample with 3 replicates

Antimicrobial Assays

PACKAGE PER SAMPLE

Type of works	Description	Price (RM) - Internal UM user	Price (RM) - External UM user	Condition / number of sample
Disc Diffusion Assay	Qualitative assessment of antimicrobial activity	250	350	1 sample against 1 type of microbial with 3 replicates
Broth Dilution Method	Determine minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC)	250	350	1 sample against 1 type of microbial with 3 replicates

Bacteria: Bacillus subtilis, Streptococcus pyrogenes

Fungi: Candida Albicans, Aspergillus niger

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